5-hydroxy-isoxazolo[4,5-b]pyrazine-3-carboxylic acid methyl - Names and Identifiers
Name | Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate
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Synonyms | METHYL 5-HYDROXYISOXAZOLO[4,5-B]PYRAZINE-3-CARBOXYLATE 5-hydroxy-isoxazolo[4,5-b]pyrazine-3-carboxylic acid methyl Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate Isoxazolo[4,5-b]pyrazine-3-carboxylic acid, 4,5-dihydro-5-oxo-, methyl ester
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CAS | 1374986-04-5
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5-hydroxy-isoxazolo[4,5-b]pyrazine-3-carboxylic acid methyl - Physico-chemical Properties
Molecular Formula | C7H5N3O4
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Molar Mass | 195.13 |
Density | 1.78±0.1 g/cm3(Predicted) |
pKa | 8.50±0.20(Predicted) |
5-hydroxy-isoxazolo[4,5-b]pyrazine-3-carboxylic acid methyl - Upstream Downstream Industry
5-hydroxy-isoxazolo[4,5-b]pyrazine-3-carboxylic acid methyl - Introduction
Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate, also known as Methyl formate 5-oxo-4,5-dihydroisoxazolo[4,5-b] pyrazine-3-carboxylic acid Methyl ester. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C8H6N2O4
-Molecular weight: 194.15g/mol
-Solubility: Soluble in some organic solvents such as ethanol and chloroform, slightly soluble in water.
Use:
- Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate can be used as intermediates in organic synthesis.
-It can be used as an important compound in drug synthesis and biological activity research.
Method:
The preparation method of Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate is not common. A possible synthetic route is as follows:
1. React isoxazoledione with methanol to generate methyl isoxazole [4,5-b] pyrazine -3-carboxylate.
2. Under alkaline conditions, Methyl isoxazole [4,5-b]pyrazine-3-carboxylate is reacted with sodium hydroxide to obtain Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate.
Safety Information:
- Methyl 5-oxo-4,5-dihydroisoxazolo[4,5-b]pyrazine-3-carboxylate is a chemical and should be used in accordance with laboratory safety procedures.
-Be careful to avoid contact with oxidizing agents during use or storage.
-Keep away from fire and high temperature to avoid harmful gas.
-Wear appropriate personal protective equipment during operation, such as chemical protective glasses and gloves.
-If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical assistance.
Last Update:2024-04-09 19:05:55